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Maulucci, G
In the context of glutamine metabolism, the downregulation of glutamine synthetase (GS) in GBM cells, prompts their dependence on glutamine uptake [16,17,18] with the increased expression of glutamine transporters (ASCT2 and SNAT3) [19, 20]
By detecting cell apoptosis, it was found that oxymatrine can enhance the expression of cleaved asparaginase 3 and Bax, and attenuate the expression of Bcl-2, which further leads to the increase of apoptosis, indicating that oxymatrine can increase the vulvar scale
This is the central mechanism most reviews focus on
The final way is through intravenous treatment, also known as IV therapy
JAMA 283(15):20082012 Taylor R, Osuch EA, Schaefer B et al (2017) Neurometabolic abnormalities in schizophrenia and depression observed with magnetic resonance spectroscopy at 7 T
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